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CAS NO.50-50-0
Estradiol Benzoate, Estradiol Valerate, Depofemin, 17α-Estradiol, Estriol, Dienogestrel, Medrogestone, ......
Estradiol benzoate
DMF available
Capacity: 1~2MT per Year
CAS: 50-50-0
Molecule Formula: C25H28O3
Molecule Weight: 376.49
Molecule Structure:
Other Name:
3-Benzoyloxy-17β-estrol; EstradiolBenzoate (AS); EstradiolBenzoate,Powder,BP; 17-Estradiol-d33-Benzoate; (8R,9S,13S,14S,17S)-17-hydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenChemicalbookanthren-3-ylbenzoate; Estra-1,3,5(10)-triene-3,17-diol(17b)-3-benzoate;EstradiolBenzoate
Estradiol benzoate Usage And Synthesis
Chemical Properties White solid
Uses antiacne, antineoplastic
Uses Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.
Definition ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Clinical Use Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.
Safety Profile Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.