shanxiyuhong(expird)
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CAS NO.1670-14-0
| Biological Activity | Benzamidine hydrochloride is a reversible, competitive inhibitor of trypsin-like serine proteases. Ki values for uPA, trypsin, trypsin-like and factor Xa were 97 µM, 21 µM, 20 µM and 110 µM, respectively. |
| Target spot | Ki: 97 µM (uPA), 21 µM (trypsin), 20 µM (tryptase), 110 µM (factor Xa) |
| Vitro Study | Benzamidine hydrochloride has weak inhibition for tPA and thrombin, with K i s of 750 µM and 320 µM, respectively. |
| Usage | Biochemical research |
|
Category |
Poison |
|
toxicity grading scale |
Poisoning |
| Acute Toxicity | Abdominal cavity - Mouse LD50: 580 mg/kg |
| Flammability hazard characteristics | Combustible; Combustion produces toxic nitrogen oxides, chloride and hydrogen chloride fumes |
| Storage and transport properties | Ventilated low temperature drying |
| Fire Extinguishing Agent | Dry powder, foam, sand, carbon dioxide, water mist |