Keywords

• 1H-BENZIMIDAZOLE,5-METHOXY-2-[[(4-METHOXY-3,5-
• SodiuM(S)-6- Methoxy-2-(((4 -Methoxy-3,5-diMethylpyr
• APIs, pharmaceutical ingredients, pharmaceutical interm

Quick Details

• ProName: Esomeprazole sodium CAS NO.161796-78-7
• CasNo: 161796-78-7
• Molecular Formula: ?C17H18N3NaO3S
• Appearance: white powder
• Application: Used in Synthesis, Pharmaceuticals
• DeliveryTime: within 7 days
• PackAge: bag or carton
• Port: xingang
• ProductionCapacity: 100 Kilogram/Day
• Purity: 99%
• Storage: Store in dry, dark and ventilated plac...
• Transportation: sea air
• LimitNum: 1 Kilogram

Superiority

• ProName: Esomeprazole sodium
• CasNo: 161796-78-7
• Molecular Formula: C17H18N3NaO3S
• Appearance: white or off-white powder
• Application: Editing of gastroesophageal reflux dis...
• DeliveryTime: Within 3 days after receiving the paym...
• PackAge: 25kg/drum
• Port: Tianjin
• ProductionCapacity: 20 Metric Ton/Year
• Purity: ≧98%
• Storage: Store in Cool and dry place, keep away...
• Transportation: By TNT, EMS, Fedex, etc.
• LimitNum: 1 Kilogram

Details

synonyms:

1h-benzimidazole,5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt; esomeprazole sodium; esomeprazoleandsalts; 5-methoxy-2- ((s)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1h-benzimidazole sodium salt;(s)-omeprazole sodium; sodium(s)-6- methoxy-2-(((4 -methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide;odium(r)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide

main functions:

1 indications editing of gastroesophageal reflux disease (gerd) - prevent erosive reflux esophagitis therapy has been cured of esophagitis in patients with long-term maintenance treatment of gastroesophageal reflux disease recurrence (gerd) symptom control and appropriate antimicrobial therapy combined with medication for eradication of helicobacter pylori, and - healing correlation of helicobacter pylori infection and prevention - related duodenal ulcer with helicobacter pylori peptic ulcer recurrence.

esomeprazole is s- optical isomer of omeprazole, is the first global isomers of proton pump inhibitor (ppi), through specific inhibition of gastric parietal cell proton pump to reduce gastric acid secretion. by a large number of clinical experiments and drug research confirmed: the maintenance of ph>4 in stomach for longer, acid suppression efficiency is higher, the efficacy is better than the former two generation ppi, the individual difference is small. as a new generation of ppi, has been widely used in clinical treatment of many acid related diseases.

proton pump inhibitor (ppi) is the drug of choice for treatment of esophageal gastric peptic ulcer and reflux disease in acid related diseases. at present, clinical on commonly used ppi omeprazole, lansoprazole, ray bella azole, pantoprazole and esomeprazole 5. omeprazole as the first ppi drug, its efficacy in the treatment of acid related diseases has been endorsed unanimously. esomeprazole, commodity name nexium (nexium), is a single heterogeneous omeprazole, namely (s) - isomer. because of its metabolic advantage, esomeprazole than omeprazole has higher bioavailability and more consistent pharmacokinetics, put the drug where proton pump increases, acid suppression effect is better than that of other ppi.

although oral esomeprazole can obtain good clinical results, but in some patients, such as patients in the recovery stage and the surgery difficulty swallowing, vomiting, acute hemorrhage of upper digestive tract, oral become a feasible way of administration of intravenous route of administration, it has become an inevitable choice. therefore, ppi does not apply to oral dosing in patients with esomeprazole sodium for injection.

molecular formula：c17h18n3nao3s

molecular weight：369.41g/mol

boiling point: 600℃ at 760mmhg

flash point: 316.7℃