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CAS NO.117704-25-3
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doramectin is a biosynthetic avermectin derived from a mutant of the original streptomyces avermitilis strain supplemented with a cyclohexylcaboxylic acid starting unit. doramectin was developed as an anthelmintic for internal parasite control. the presence of the cyclohexyl group replacing the sec-butyl moiety affords greater hydrophobicity and longer biological half-life compared to avermectin. like the other milbemycin/avermectins, it selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite.
cas no.:
117704-25-3
other names:
doramectin
mf:
c50h74o14
type:
antibiotic and antimicrobial agents
grade standard:
medicine grade
usage:
animal pharmaceuticals
brand name:
hhd
model number:
hhd090
purity:
99%min
molecular weight:
899.1142
inchi:
inchi=1/c50h74o14
boiling point:
967.4°c at 760 mmhg
density:
1.25g/cm3
flash point:
274.4°c
refractive index:
1.579
vapour pressur:
0mmhg at 25°c
physical state:
solid
storage:
store at -20° c
pk values:
-12.42