Keywords

• Baclofen
• Baclofen powder
• 1134-47-0

Quick Details

• ProName: Baclofen CAS 1134-47-0 Medicine Grade ...
• CasNo: 1134-47-0
• Molecular Formula: white powder
• Appearance: white powder
• Application: Used in Synthesis, Pharmaceuticals
• DeliveryTime: within 7 days
• PackAge: bag or carton
• Port: xingang
• ProductionCapacity: 100 Kilogram/Day
• Purity: 99%
• Storage: Store in dry, dark and ventilated plac...
• Transportation: sea air
• LimitNum: 1 Kilogram

Superiority

• ProName:Baclofen CAS 1134-47-0 Medicine Grade...
• CasNo:1134-47-0
• Appearance:white powder
• Application:pharmaceutical raws
• DeliveryTime:1-3 Days
• PackAge:25kgs/Drum
• Port:Shanghai
• ProductionCapacity:2 Metric Ton/Month
• Purity:99%
• Transportation:By air or by sea
• LimitNum:100 Gram

Details

What is  Baclofen

Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA).
A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.

Function of Baclofen

Baclofen powder can be used as Specific GABA-B receptor agonist. Muscle relaxant (skeletal). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.