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CAS NO.53716-49-7
1. specification of carprofen
| items | specifications | results |
| appearance | white or almost white crystalline powder | conforms |
| identification | infrared absorption spectrum corresponds to that of the reference standard | conforms |
| appearance of solution | the solution is clear and not more than intensely coloured than reference solution by3 | conforms |
| loss on drying | not more than 0.5% | 0.23% |
| sulphated ash | not more than 0.1% | 0.07% |
| heavy metals | not more than 0.002% | conforms |
| related substances | ||
| unspecified impurities | not more than 0.2% | 0.17% |
| total impurities | not more than 0.5% | 0.39% |
| assay | 98.5%~101.5% on the dried basis | 99.30% |
| residual solvents | ||
| acetone | not more than 5000ppm | not detected |
| organic volatile impurity | ||
| methylene chloride | not more than 500ppm | not detected |
| conclusion | the results can conform to ep6 |
2. usage for carprofen
1) carprofen (marketed as rimadyl, imadyl, novox, imafen and rovera, is a non-steroidal anti-inflammatory drug
that veterinarians prescribe as a supportive treatment for various conditions.
2) it provides day-to-day treatment for pain and inflammation from arthritis in geriatric dogs, joint pain, osteoarthritis,
hip dysplasia, and other forms of joint deterioration.